Dry goods|What preparations are needed for the uterus before embryo transfer? -American Surrogacy Network Meiguodaiyun American Surrogacy | American Surrogacy Network | American IVF | American Surrogacy

Dry goods|What preparations are needed for the uterus before embryo transfer?

5/6/2020

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When it comes to surgery, expectant mothers will be unconsciously afraid.In fact, the test tube baby transplantation operation is very simple, that is, placing the embryo in a long and thin transplantation tube, and then placing the embryo in the tube under the guidance of B ultrasound into the uterine cavity, thus completing the entire transplantation operation from the beginning to the It usually only takes about 15 minutes to finish.

However, what kind of preparation is needed for the uterus before the IVF transplant?

I believe that after reading the following text, it can help you better understand the test tube baby in the United States and better prepare for pregnancy.

Accepted endometrium

Dry goods|What preparations are needed for the uterus before embryo transfer?

For women, the thickness of the endometrium changes with the menstrual cycle, and the normal thickness is different in different periods. Generally speaking, the thickness of endometrium in women during ovulation is between 8mm-12mm.

Endometrial ultrasound morphology (including endometrial thickness, echo, blood flow, etc.) is an important evaluation index to judge the implantation window period of embryo transfer.

Ultrasound shows that the thickness of the normal endometrial implant window is generally between 7-10mm, the volume should not be less than 2ml, and the endometrial energy Doppler area is more than 5㎜.

Many studies have shown that if a woman’s endometrium is not thick enough, it is not conducive to women’s pregnancy. When the thickness of the endometrium is 8mm, the embryo is most likely to be implanted. It does not matter if it is lower than 8mm.

It should be noted that when the thickness of the endometrium is less than 6 mm, successful pregnancy of the embryo is difficult.

When the thickness of the female endometrium is not enough to conceive, generally different methods will be tried for treatment. But what if the problem persists?

One way is to cancel the embryo transfer, continue to take medication for the problems of the uterus and try again later.

age

solution:

Usually supplemented with growth hormone to regulate

Hormone secretion

solution:

Estrogen supplementation from the second day of menstruation

Corpus luteum function

solution:

Progesterone hormone supplementation after ovulation

Intimal injury

solution:

Treatment of cold instruments under hysteroscope, endometrial transplantation is needed in severe cases

The second option is to continue the transplant.

Thin endometrium does not necessarily mean that pregnancy is impossible, but the pregnancy success rate may be reduced. This attempt is mainly to use this opportunity to conduct additional tests to assess the "acceptability" or ability of the uterus in preparation for the next embryo implantation.

But in general, we do not use this program lightly, especially for older women with poor egg quality: womenEvery egg is very precious.

The specific treatment plan needs to be formulated according to the actual situation of the patient.

The right time to transplant

In order for the embryo to implant successfully in the uterus, the correct time must be selected for transplantation.

The so-called correct time, we call it the "transplant window period". If this time is missed, it can lead to uneven distribution of embryos in the uterus, blocked embryogenesis, embryo absorption, and fetal growth retardation. Therefore, accurately grasping the transplantation window period is conducive to the successful implantation of embryos and improves the success rate of IVF.

U.S. test-tube baby embryo transfer generally monitors egg growth and maturity by B-ultrasound. After the conditions for egg retrieval are met, a broken needle is injected one night before the egg retrieval operation to help the egg mature and release the signal of ovulation to the body. Subsequently, the doctor will implant the embryo The best time to enter is for you to complete the transplant operation.

Secondly, the activity of the endometrial blood vessels will change periodically. When the endometrium is gradually increased at the end of diastolic blood flow in the uterus, the mid-luteal phase reaches a peak, and the resistance index drops significantly, it will also be very conducive to embryo implantation. .

Suitable uterine environment

Endometrial cells are constantly producing fluids.

Some of these fluids are reabsorbed by cells in the endometrium, some fluids leak from the uterus through the cervix into the vagina, and some leaks are considered to be fallopian tubes into the abdomen. However, in some cases, additional fluid may accumulate in the cavity, which can be seen on ultrasound.

We do not want to transfer embryos into the fluid-filled uterine cavity, because this will reduce the chance of embryo implantation.

The accumulation of fluid in the uterine cavity of some patients may be a sign of obstruction of the end of the fallopian tube, which is called hydrosalpinx in clinical treatment.

Hydrosalpinx is also a very important factor affecting the success of IVF transplantation.

In general, expectant mothers with hydrosalpinx have a much lower chance of pregnancy during the IVF cycle.

We generally solve this factor of unsuccessful pregnancy through tubal dredge and salpingectomy.

Other unknown issues

There are many complex interactions between the endometrium and the embryo. Even if the problems described above do not exist, the embryo may still not be implantable. With the deepening of research, it is expected to discover new problems and new therapies.

Dry goods|What preparations are needed for the uterus before embryo transfer?

The advent of the little angel is a very difficult thing.

In addition to the above conditions, you also need:

One is to break through psychological barriers and maintain a good attitude.

Face the treatment process calmly, maintain communication and communication without any psychological burden.Especially for women, high psychological pressure and nervous tension may cause uterine muscle contraction disorders and embryos cannot implant normally, resulting in failure to transplant, so you must maintain a happy mood.

The second is to develop healthy habits.

Quit smoking alcohol in the first half of the test tube, because nicotine and alcohol will not only cause male oligospermia, weak sperm, sperm deformity, but also affect female ovarian function;

Scientific diet, do not eat fried foods, eat more fruits and vegetables and whole grains;

Appropriate exercise to enhance physical fitness;

Adjust bad habits (such as staying up late) and so on.