Infertile women who are test-tube babies must not be too familiar with the term "blastocyst". "Blastocyst" is an embryo that is cultivated to the fifth day after fertilization. Doctors often use embryonic culture to metaphorize sports training. Successful fertilization is through In the preliminary round, every day is a rematch. The embryos will be eliminated continuously. Finally, the blastocyst will be equivalent to the final. This means that these are embryos that have passed the test. The chance of pregnancy after implantation will of course be higher.

"What are the benefits of culturing blastocysts?"

XNUMX. The progress of embryo growth is easier to synchronize with the endometrium

XNUMX. The normal embryo will return to the uterine cavity on the fifth day, and the blastocyst stage implantation is closest to the natural physiological condition

XNUMX. The uterine contraction is reduced, reducing the possibility of the embryo being discharged

XNUMX. It is easy to classify embryos, which is helpful for embryo selection

XNUMX. Eliminate bad embryos, increase implantation rate, reduce abortion rate, and reduce the time it takes to successfully conceive

Sixth, implanting a single blastocyst can avoid multiple births

XNUMX. Chromosome pre-implantation chromosome examination (PGS/PGT-A) can be done, with less damage to the embryo

"Can I get pregnant by implanting a blastocyst?"

Although blastocysts represent better embryos, which can increase the chance of success, they may actually be unhealthy embryos. After implantation, they cannot become pregnant or miscarry after pregnancy. The main key is whether the chromosomes are normal, which is related to age. The study found that half of the blastocysts of women younger than 40 years old had normal chromosomes, and more than 40% of them were less than XNUMX years old (the blastocyst grade was not considered). Many doctors worry that the in vitro culture will be damaged, so it is not wrong to stop the culture on the third day, but the reality is that most embryos that have been successfully fertilized can live to the third day, it is not easy to distinguish which may be able to let you Pregnant embryos, this is actually gambling luck.

"If you want to get a blastocyst with normal chromosomes, how many eggs do you need to take?"

Let's take a look at the simple prediction formula given by Danish professor Peter Humaidan based on literature data: 

Using this formula plus the ratio of normal blastocysts of various ages, we can know that a few years old women need a few eggs to get a blastocyst with normal chromosomes.

举例来说，依照公式反推33岁女性需要6颗卵才能得到1颗染色体正常的囊胚；40岁女性则需要10颗卵才能得到1颗染色体正常的囊胚，这也就是为什么40岁女性常常需要不只一次试管疗程。

Assuming that 10 eggs are also taken, a 33-year-old woman can get two chromosomal blastocysts; a 2-year-old woman can only get one chromosomal blastocyst.

It can be seen that the older you need, the more eggs you need to get an embryo with normal chromosomes, but this is the average probability, it is possible to get just one egg and it is just a healthy egg (luck must be super good), but if you are old And there are not many eggs, so it is still possible to consider collecting eggs or embryos clinically. After all, every implantation will delay a lot of time, and the next time you take it, you will be a few months old.

 "Am I suitable for raising blastocysts?"

Regardless of age, AMH value, and the number of basic follicles, everyone can try to culture blastocysts. Although it is hoped that we can weaken and stay strong, and screen embryos that are more likely to be pregnant, but old age, fewer eggs, chromosomal abnormalities, and genetic diseases Women and men with few sperm, poor motility, or abnormal sperm ratio may have no embryo implantation, the doctor will still give advice according to each person's conditions, so be sure to contact your The doctor discusses whether blastocyst cultivation is suitable for you!

The last thing to remind everyone is:
XNUMX. Although more eggs are better, mature eggs are the only ones that can be used, so don’t get me wrong if you get more eggs.

XNUMX. A blastocyst with a normal chromosome does not necessarily mean that it can implant smoothly. If the embryo grade is not good, even if the PGS report is normal, it may not be able to successfully conceive or abort.

XNUMX. This formula cannot be applied to everyone, even the same person, different cycle conditions, different treatments, and different laboratories will affect the final embryonic results!